Introduction High-throughput technologies have revolutionized the understanding of rheumatoid arthritis (RA), revealing new molecular and cellular pathways in tissue inflammation. Fibroblasts, long studied in RA, have gained renewed attention as…
Introduction Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes inflammation in the joints, leading to pain, stiffness, and progressive disability. It affects nearly 2% of the global population,…
Introduction Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting about 1% of the population, mainly women, and significantly increases cardiovascular disease (CVD) risk, shortening lifespan by 5–18 years. Despite…
Introduction (Article introduction authored by Conquest Editorial Team) Seropositive rheumatoid arthritis (RA) arises from a complex interplay of genetic and environmental factors, with most patients having no family history of…
Introduction (Article introduction authored by Conquest Editorial Team) A clinical practice guideline (CPG) was developed to provide podiatric recommendations for managing rheumatoid arthritis (RA), focusing on conservative care. The guideline…
Introduction (Article introduction authored by Conquest Editorial Team) A variety of disease-modifying antirheumatic drugs (DMARDs) are now available for treating rheumatoid arthritis (RA), including biologic DMARDs (bDMARDs) such as TNF…
Introduction (Article introduction authored by Conquest Editorial Team) Rheumatoid arthritis (RA) poses a diagnostic challenge due to its diverse clinical manifestations, ranging from polyarthritis to systemic complications. PET/CT imaging, particularly…
Introduction (Article introduction authored by Conquest Editorial Team) In recent years, significant strides have been made in understanding the genetic, environmental, and immunological factors contributing to rheumatoid arthritis (RA). Detection…
Introduction (Article introduction authored by Conquest Editorial Team) Over the past two decades, treatment options for rheumatoid arthritis (RA) have evolved significantly. Methotrexate (MTX), biologic disease-modifying antirheumatic drugs (bDMARDs), and…
Introduction Rheumatoid arthritis (RA) stands as a multifaceted autoimmune disorder marked by persistent inflammation impacting the synovial tissues of numerous joints. Granzymes (Gzms) are serine proteases that are unleashed into…
