Introduction The study aimed to assess adherence to immunosuppressive medications among kidney transplant patients (KTPs) and to compare adherence rates for tacrolimus, cyclosporine, and sirolimus. Out of 63 patients treated…
Introduction Kidney transplantation is the gold standard treatment for end-stage kidney disease, significantly improving patient survival and quality of life. However, transplant patients require immunosuppression to prevent rejection, which increases…
Introduction Uremic pruritus is a common itching symptom in chronic kidney disease, especially in patients on hemodialysis. Its exact cause is unclear and likely multifactorial. Prevalence varies widely (25%–73%) due…
Introduction Renal allograft dysfunction, presenting as either acute or gradual loss of kidney function, remains a major complication following transplantation. These conditions often progress silently and are typically detected through…
Introduction Inflammation plays a central role in determining transplant outcomes. Its intensity varies across living donation, DBD, DCD, and xenotransplantation, with pig xenografts provoking the strongest systemic inflammatory response. Inflammation…
Introduction Renal allograft dysfunction, presenting as either acute or gradual loss of kidney function, remains a major complication following transplantation. These conditions often progress silently and are typically detected through…
Introduction Extracorporeal photopheresis (ECP) is an emerging immunomodulatory therapy that promotes donor-specific tolerance, reduces alloimmunity, and minimizes the need for long-term immunosuppression in transplant patients. It works by inducing apoptosis…
Introduction Kidney transplantation remains the preferred treatment for end-stage kidney disease, offering superior survival and quality of life compared to dialysis. Advances such as broader organ sharing, paired donor exchanges,…
Introduction Calcineurin inhibitors (CNIs), particularly tacrolimus, have long been the cornerstone of maintenance immunosuppression following liver transplantation (LT). While effective in preventing graft rejection, CNIs are frequently associated with significant…
Introduction Calcineurin inhibitors (CNIs), primarily tacrolimus, are widely used as standard maintenance immunosuppressants in liver transplant (LT) recipients. However, their long-term use is often associated with significant adverse effects such…
