Introduction Acquired aplastic anemia (AA) is an immune-mediated bone marrow failure caused by a cytotoxic T-cell attack on hematopoietic stem cells. Diagnosing AA requires ruling
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Nephrology is a specialty of medicine and pediatric medicine that concerns with study of the kidneys, specifically normal kidney function and kidney disease, the preservation of kidney health, and the treatment of kidney disease, from diet and medication to renal replacement therapy.
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The Role of Semaphorins in the Pathogenesis of Rheumatoid Arthritis
Introduction Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes inflammation in the joints, leading to pain, stiffness, and progressive disability. It affects nearly
Management of kidney transplant recipients for primary care practitioners
Introduction Patients with kidney transplants face significant health challenges due to a high burden of pre-existing conditions and the use of immunosuppressive medications. These factors
Introduction Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting about 1% of the population, mainly women, and significantly increases cardiovascular disease (CVD) risk, shortening
Novel Approaches to Immunomodulation for Solid Organ Transplantation
Introduction Despite significant advances in the field of transplantation in the past two decades, current clinically available therapeutic options for immunomodulation remain fairly limited. The
Introduction (Article introduction authored by Conquest Editorial Team) Over the past 50 years, aplastic anemia (AA) treatment has transformed from a fatal diagnosis to one
Identification of early risk factors for anti-citrullinated-protein-antibody positive rheumatoid arthritis – A prospective cohort study
Introduction (Article introduction authored by Conquest Editorial Team) Seropositive rheumatoid arthritis (RA) arises from a complex interplay of genetic and environmental factors, with most patients
A clinical practice guideline for the management of the foot and ankle in rheumatoid arthritis
Introduction (Article introduction authored by Conquest Editorial Team) A clinical practice guideline (CPG) was developed to provide podiatric recommendations for managing rheumatoid arthritis (RA), focusing