Introduction High-throughput technologies have revolutionized the understanding of rheumatoid arthritis (RA), revealing new molecular and cellular pathways in tissue inflammation. Fibroblasts, long studied in RA,
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Nephrology is a specialty of medicine and pediatric medicine that concerns with study of the kidneys, specifically normal kidney function and kidney disease, the preservation of kidney health, and the treatment of kidney disease, from diet and medication to renal replacement therapy.
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Future of non-invasive graft evaluation: A systematic review of proteomics in kidney transplantation
Introduction Kidney transplantation (KT) remains the most common solid organ transplant, with over 25,000 procedures performed annually. Despite the increasing number of transplants, long-term graft
Introduction Intra-patient variability (IPV) in tacrolimus blood concentrations has emerged as a potential biomarker for managing organ transplant patients. This study explored the relationship between
Introduction Diabetes mellitus (DM) in kidney transplant recipients (KTR) significantly increases the risk of mortality, infections, and long-term graft loss. Early identification and prevention strategies,
Machine Perfusion in Deceased Donor Kidney Transplantation: Editorial Summary of a Cochrane Review
Introduction Kidney transplantation is the best treatment for kidney failure, offering better survival and quality of life than dialysis. However, donor organ availability remains a
Introduction Allogeneic hematopoietic cell transplantation (HCT) is a curative treatment for severe aplastic anemia (SAA), but specific transplant guidelines have been lacking. A panel of
The state of the art in the treatment of severe aplastic anemia: immunotherapy and hematopoietic cell transplantation in children and adults
Introduction Acquired aplastic anemia (AA) is an immune-mediated bone marrow failure caused by a cytotoxic T-cell attack on hematopoietic stem cells. Diagnosing AA requires ruling
The Role of Semaphorins in the Pathogenesis of Rheumatoid Arthritis
Introduction Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes inflammation in the joints, leading to pain, stiffness, and progressive disability. It affects nearly