Introduction (Article introduction authored by Conquest Editorial Team) Advancements in immunosuppression have significantly improved outcomes for kidney transplant recipients (KTR), particularly in graft survival. The introduction of cyclosporine and anti-thymocyte…
Introduction (Article introduction authored by Conquest Editorial Team) In kidney transplantation, day-zero biopsies are used to assess organ quality and discriminate between donor-inherited lesions and those acquired post-transplantation. However, many…
Introduction (Article introduction authored by Conquest Editorial Team) The kidney is crucial for filtering waste from the body, with renal transplantation being the primary treatment for end-stage renal failure. Graft…
Introduction (Article introduction authored by Conquest Editorial Team) Kidney transplantation stands as the gold standard for treating end-stage renal diseases (ESRDs), offering a life-saving solution for patients. However, the persistent…
Introduction (Article introduction authored by Conquest Editorial Team) Balancing immunosuppression in kidney transplant recipients (KTRs) is challenging. Standard triple-drug therapy (tacrolimus, mycophenolate mofetil, and corticosteroids) is common, but minimizing immunosuppression…
Introduction (Article introduction authored by Conquest Editorial Team) Antibody-mediated rejection (AMR) has been- recognized as a prominent contributor to acute and chronic kidney allograft dysfunction, eventually leading to graft failure.…
Introduction (Article introduction authored by Conquest Editorial Team) The ELITE-Symphony study findings have influenced KDIGO guidelines for renal transplant immunosuppressive therapy. Current recommendations include induction therapy with tacrolimus, mycophenolate, and…
Introduction (Article introduction authored by Conquest Editorial Team) Despite advances in immunosuppressive treatments-, kidney transplant rejection remains a significant challenge impacting graft longevity. This article provides an overview of the…
Introduction In recent years, advancements in understanding allorecognition and graft rejection mechanisms have revealed a complex immune response involving multiple pathways. Current transplant monitoring relies on traditional markers such as…
Introduction Chronic kidney disease (CKD) affects a significant number of individuals worldwide and is projected to become a leading cause of death in the future. The shortage of kidney donors…
