Introduction Calcineurin inhibitors (CNIs), particularly tacrolimus, have long been the cornerstone of maintenance immunosuppression following liver transplantation (LT). While effective in preventing graft rejection, CNIs are frequently associated with significant…

Introduction Calcineurin inhibitors (CNIs), primarily tacrolimus, are widely used as standard maintenance immunosuppressants in liver transplant (LT) recipients. However, their long-term use is often associated with significant adverse effects such…

The study by Lee et al., published in Clinical and Molecular Hepatology, offers important insights into the long-term risks of chronic kidney disease (CKD) and end-stage renal disease (ESRD) among…

Introduction Kidney transplantation (KT) remains the most common solid organ transplant, with over 25,000 procedures performed annually. Despite the increasing number of transplants, long-term graft survival has stagnated due to…

Introduction Diabetes mellitus (DM) in kidney transplant recipients (KTR) significantly increases the risk of mortality, infections, and long-term graft loss. Early identification and prevention strategies, especially for patients on the…

Introduction Kidney transplantation is the best treatment for kidney failure, offering better survival and quality of life than dialysis. However, donor organ availability remains a challenge. In deceased donor transplantation,…

Introduction Patients with kidney transplants face significant health challenges due to a high burden of pre-existing conditions and the use of immunosuppressive medications. These factors increase their risk for complications…

Introduction Despite significant advances in the field of transplantation in the past two decades, current clinically available therapeutic options for immunomodulation remain fairly limited. The advent of calcineurin inhibitor–based immunosuppression…

Introduction (Article introduction authored by Conquest Editorial Team) Drugs offer therapeutic benefits but can also cause adverse drug reactions (ADRs), ranging from mild to severe, including disability and death. Clinical…

Introduction (Article introduction authored by Conquest Editorial Team) Cognitive impairment is common in kidney failure patients, impacting their eligibility for kidney transplant (KT), quality of life, and survival. While cognitive…