Introduction Inflammation plays a central role in determining transplant outcomes. Its intensity varies across living donation, DBD, DCD, and xenotransplantation, with pig xenografts provoking the strongest systemic inflammatory response. Inflammation…

Introduction Renal allograft dysfunction, presenting as either acute or gradual loss of kidney function, remains a major complication following transplantation. These conditions often progress silently and are typically detected through…

Introduction Extracorporeal photopheresis (ECP) is an emerging immunomodulatory therapy that promotes donor-specific tolerance, reduces alloimmunity, and minimizes the need for long-term immunosuppression in transplant patients. It works by inducing apoptosis…

Introduction Kidney transplantation remains the preferred treatment for end-stage kidney disease, offering superior survival and quality of life compared to dialysis. Advances such as broader organ sharing, paired donor exchanges,…

Introduction Calcineurin inhibitors (CNIs), particularly tacrolimus, have long been the cornerstone of maintenance immunosuppression following liver transplantation (LT). While effective in preventing graft rejection, CNIs are frequently associated with significant…

Introduction Calcineurin inhibitors (CNIs), primarily tacrolimus, are widely used as standard maintenance immunosuppressants in liver transplant (LT) recipients. However, their long-term use is often associated with significant adverse effects such…

The study by Lee et al., published in Clinical and Molecular Hepatology, offers important insights into the long-term risks of chronic kidney disease (CKD) and end-stage renal disease (ESRD) among…

Introduction Kidney transplantation (KT) remains the most common solid organ transplant, with over 25,000 procedures performed annually. Despite the increasing number of transplants, long-term graft survival has stagnated due to…

Introduction Diabetes mellitus (DM) in kidney transplant recipients (KTR) significantly increases the risk of mortality, infections, and long-term graft loss. Early identification and prevention strategies, especially for patients on the…

Introduction Kidney transplantation is the best treatment for kidney failure, offering better survival and quality of life than dialysis. However, donor organ availability remains a challenge. In deceased donor transplantation,…