Introduction Graft-versus-host disease (GVHD) is a major barrier to the success of hematopoietic stem cell transplantation (HSCT), affecting both survival and quality of life. Macrophages
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Nephrology is a specialty of medicine and pediatric medicine that concerns with study of the kidneys, specifically normal kidney function and kidney disease, the preservation of kidney health, and the treatment of kidney disease, from diet and medication to renal replacement therapy.
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Rapid Response with Daratumumab for Pure Red Cell Aplasia in a Case of Aplastic Anemia with Mixed Chimerism After ABO-Mismatched Stem Cell Transplant
Introduction Pure red cell aplasia (PRCA) is a rare but serious complication occurring in 7–10% of patients after major ABO-mismatched allogeneic stem cell transplantation (HSCT),
Combination therapy: an upcoming paradigm to improve kidney and cardiovascular outcomes in chronic kidney disease
Introduction Calcineurin inhibitors (CNIs), particularly tacrolimus, have long been the cornerstone of maintenance immunosuppression following liver transplantation (LT). While effective in preventing graft rejection, CNIs
Introduction Calcineurin inhibitors (CNIs), primarily tacrolimus, are widely used as standard maintenance immunosuppressants in liver transplant (LT) recipients. However, their long-term use is often associated
Introduction Tocilizumab (TCZ), a monoclonal antibody targeting the IL-6 receptor, has become a cornerstone therapy in rheumatoid arthritis (RA) management. It effectively reduces inflammation and
The study by Lee et al., published in Clinical and Molecular Hepatology, offers important insights into the long-term risks of chronic kidney disease (CKD) and
Introduction Healthcare inequality remains a significant challenge, affecting treatment access and clinical outcomes for various patient groups. In rheumatoid arthritis (RA), disparities in the initiation
Introduction High-throughput technologies have revolutionized the understanding of rheumatoid arthritis (RA), revealing new molecular and cellular pathways in tissue inflammation. Fibroblasts, long studied in RA,
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