Graft Versus Host Disease
Graft Versus Host Disease(GVHD) is a life-threatening condition in which body is attacked by donor immune cells after a patient undergoes an allogeneic stem cell or bone marrow transplant.
Graft Versus Host Disease
Graft Versus Host Disease(GVHD) is a life-threatening condition in which body is attacked by donor immune cells after a patient undergoes an allogeneic stem cell or bone marrow transplant.
UNDERSTANDING THE DIFFERENCE
UNDERSTANDING THE DIFFERENCE
GVHD can be chronic or acute. Chronic GVHD (cGVHD) usually starts more than three months after a transplant and can last a lifetime. Acute GVHD (aGVHD) can occur soon after a transplant.
GVHD can be chronic or acute. Chronic GVHD (cGVHD) usually starts more than three months after a transplant and can last a lifetime. Acute GVHD (aGVHD) can occur soon after a transplant.
ACUTE GVHD SYMPTOMS
Skin rash
Jaundice
Nausea
Vomiting
Abnormal blood test results
Diarrhea
Abdominal cramping
chronic GVHD SYMPTOMS
Tightness in joints
Vaginal dryness
Weight loss
Abdominal swelling
Difficulty swallowing
Skin rash & thickening
Raised or discolored areas
Dry & white patches inside mouth
Fatigue & muscle weakness
ACUTE GVHD SYMPTOMS
Skin rash
Jaundice
Nausea
Vomiting
Abnormal blood test results
Diarrhea
Abdominal cramping
chronic GVHD SYMPTOMS
Tightness in joints
Vaginal dryness
Weight loss
Abdominal swelling
Difficulty swallowing
Skin rash & thickening
Raised or discolored areas
Dry & white patches inside mouth
Fatigue & muscle weakness
risk factors
Donor/recipient HLA(human leukocyte antigen) match, in which there are differences between the patient & donor
A female donor who has been pregnant in past
Older transplant recipients
The advanced age of either the donor or the recipient
Patients who may have already experienced acute GVHD
risk factors
Donor/recipient HLA(human leukocyte antigen) match, in which there are differences between the patient & donor
A female donor who has been pregnant in past
Older transplant recipients
The advanced age of either the donor or the recipient
Patients who may have already experienced acute GVHD
diagnosis
treatment
- Biopsy
- Imaging studies
- Immunosuppressive Drug
- Chemotherapy
- Steroid
- Antifungal Drugs
- Antiviral Drugs
- Antibiotics
diagnosis
- Biopsy
- Imaging studies
treatment
- Immunosuppressive Drug
- Chemotherapy
- Steroid
- Antifungal Drugs
- Antiviral Drugs
- Antibiotics
